Professors

Prof. Xiao-Lan Chen.pngProf. Xiao-Lan Chen

陈晓岚  教授

硕士生导师

博士生导师

郑州大学学科特聘教授(学科骨干)

[email protected]

出生年月: 1964.12

工作经历

2005-至今 郑州大学化学学院  教授

2007-至今 郑州大学河南省化学生物与有机化学重点实验室副主任

2010-至今 郑州大学化学与分子工程学院硕士生导师、博士生导师

2006-2007 美国南加州大学药物化学系访问学者

1998-2005 郑州大学化学系 副教授   硕士生导师

1987-2000 河南医科大学基础部教师

学习经历

1983-1987 郑州大学化学系本科学习

1996-1997 英国瑞丁大学化学系留学

2001-2004 郑州大学化学系博士研究生

学术头衔

河南省高等学校教学名师

郑州大学化学与分子工程学院教授委员会委员

郑州市磷化学生物学重点实验室主任

河南省天方药物化学工程实验室主任

全国磷复肥产业联盟专家

主持的部分国家级及省部级科研项目

1、基于Click反应三氮唑桥连双膦酸类化合物的设计、合成研究,国家自然科学基金(No. 21072178)

2、肿瘤靶位蛋白与磷酰化黄酮的弱相互作用研究,国家自然科学基金(No. 20472076)

3、磷酰化黄酮与蛋白弱相互作用和作用位点研究,河南省杰出青年基金项目(No. 054100001400)

4、新型抗骨质疏松双膦酸药物设计、合成及工艺优化,河南省科技创新人才计划(114200510023)

5、新型三氮唑双膦酸衍生物的合成与活性研究,郑州市科技领军人才(112PLJRC359)

6、基于Click反应1,2,3-三氮唑桥连新型双膦酸类化合物的设计、合成研究,高等学校博士学科点专项科研基金(20124101110003)

7、功能磷化合物设计合成及推广应用 (16008),河南省优秀创新型科技团队

8、自由基加成串联反应构建聚集诱导发光效应新型芳香氮杂稠环,国家自然科学基金(No. 22071222)

主持的国家级教学项目

1、有机化学双语教学,2010年国家双语教学示范课程。

2、2013 来华留学英语授课品牌课程(有机化学)。

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Education

– B. S. in Chemistry, Zhengzhou University, 1983.

– Visiting Scientist, Reading University, UK, (Director: John Mann), 1996-1997.

– Ph. D. in Organic Chemistry, Zhengzhou University, (Thesis Advisor: Zhao Yufen), 2004.

Work Experience

– Assistant Professor of Organic Chemistry, Zhengzhou University, 1987-1998.
– Associate Professor of Organic Chemistry, Zhengzhou University, 1998-2004.

– Advanced Visiting Scientist, University of Southern California, USA, (Director: Charles Mckenna), 2006-2007.

– Professor of Organic Chemistry, Zhengzhou University, 2004-present.

Research Areas

– Natural product separation, extraction and structure identification;

– Phosphorylated modification of natural product and covalent interaction of phosphorylated natural products with proteins;

– Design, synthesis, and biological evaluation of novel bisphosphonate;

– Development of novel synthetic methods by using dialkyl H-phosphonates as reaction reactant as well as catalyst and reaction promoter.

Teaching project ongoing (as project leader)

– National Brand Course In English For International Students

– 2010 National Bilingual Model Course: Organic Chemistry

Current and completed research projects

– Designs and synthesis of novel 1,2,3-Triazole linked bisphosphonates based on click chemistry. The National Natural Science Foundation of China (No. 21072178). 2011-2013.

– Synthesis and process optimization of the novel osteoporosis drugs, bisphosphonates, Innovation Specialist Projects of Henan Province (No. 114200510023). 2011-2013.

– Synthesis and activity study of the novel 1,2,3-Triazole linked bisphosphonates derivatives. Technology and Science talent Cultivation Project in Zhengzhou City (No. 112PLJRC359). 2011-2013.

– Designs and synthesis research of novel 1,2,3-Triazole linked bisphosphonates under the influence of ultrasound irradiation. Foundational and Frontier Technology Research – Foundation of Henan Province. 2013-2015.

– Designs and synthesis of novel 1,2,3-triazole linked with bisphosphonates based on click chemistry. The Special Fund for the Doctoral Program of Higher Education (No. 20124101110003). 2013-2015.

– The non-covalent interaction of tumor targeted protein with phosphorylated flavonoids. – The National Natural Science Foundation of China (No. 20472076). 2004-2006.

The study of the target of non-covalent interaction of phosphorylated flavonoids with proteins. The Science Fund for Distinguished Young of Henan Province (No. 054100001400). 2005-2007.

– The study on the phosphorylated modification of naturally occurring flavonoids and the covalent interaction of phosphorylated flavonoids with biological macromolecules, The Henan Innovation Project for University Prominent Research Talents (No. 2007KYCX011). 2007-2009.

– The 2017 Science and Technology Innovation Team in Henan Province. “The design, synthesis and application of functional phosphorus compounds”. 2017-2019.

BYu.png

Dr. Bing Yu

於兵 博士

教授(直聘)

硕士生导师

博士生导师

郑州大学青年拔尖人才

[email protected] (优先)

[email protected]

出生年月: 1987.09

工作经历

2017/11-至今, 郑州大学, 化学学院, 教师

2014/07-2017/10, 北京理工大学, 化学与化工学院, 博士后, 合作导师: 胡长文教授

2016/10-2017/05, 东京工业大学, 博士后, 合作导师: Nobuharu Iwasawa教授

2015/09-2016/09, 首尔国立大学, 博士后, 合作导师: Soon Hyeok Hong教授

学习经历

2009/09-2014/06, 南开大学, 元素有机化学国家重点实验室, 博士, 导师: 何良年教授

2005/09-2009/06, 华中师范大学, 化学生物实验班, 学士

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Work Experience

2017/11-present, College of Chemistry and Molecular Engineering, Zhengzhou University. Faculty
2014/07-2017/10, Beijing Institute of Technology, Postdoctoral Researcher, with Prof. Chang-Wen Hu
2016/10-2017/05, Tokyo Institute of Technology, Postdoctoral Researcher, with Prof. Nobuharu Iwasawa
2015/09-2016/09, Seoul National University, Postdoctoral Researcher, with Prof. Soon Hyeok Hong

Education

2009/09-2014/06, Nankai University. Ph.D., Supervised by Prof. Liang-Nian He.

2005/09-2009/06, Central China Normal University. B.Sc.

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